TargetMol

ZM 306416

Product Code:
 
TAR-T1754
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1754-2mg2mg£102.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1754-1mL1 mL * 10 mM (in DMSO)£115.00
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Quantity:
TAR-T1754-5mg5mg£115.00
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Quantity:
TAR-T1754-10mg10mg£151.00
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Quantity:
TAR-T1754-25mg25mg£238.00
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Quantity:
TAR-T1754-50mg50mg£386.00
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Quantity:
TAR-T1754-100mg100mg£540.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
ZM 306416, a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
CAS:
690206-97-4
Formula:
C16H13ClFN3O2
Molecular Weight:
333.75
Pathway:
Cytoskeletal Signaling; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9931
SMILES:
COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC
Target:
VEGFR; Bcr-Abl; Src

References

1. Antczak C, et al. J Biomol Screen, 2012, 17(7), 885-899. 2. Wilkinson J, et al. Assay Drug Dev Technol. 2011 Apr;9(2):125-35. 3. Susarla R, et al. Mol Cell Endocrinol, 2012, 351(2), 199-207. 4. Susarla R, et al. J Cell Physiol, 2012, 227(5), 11992-22002.