TargetMol

(S,R,S)-AHPC-PEG2-N3

Product Code:
 
TAR-T17913
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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Further Information

Bioactivity:
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.
CAS:
2010159-45-0
Formula:
C28H39N7O6S
Molecular Weight:
601.72
Pathway:
Others|PROTAC
Purity:
0.98
SMILES:
O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCN=[N+]=[N-]
Target:
Ligand for E3 Ligase|Others

References

1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.