TargetMol

AGI-6780

Product Code:
 
TAR-T1809
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1809-1mg1mg£95.00
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TAR-T1809-2mg2mg£106.00
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TAR-T1809-5mg5mg£128.00
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TAR-T1809-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T1809-10mg10mg£168.00
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TAR-T1809-25mg25mg£257.00
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Quantity:
TAR-T1809-50mg50mg£402.00
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TAR-T1809-100mg100mg£567.00
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Quantity:
TAR-T1809-500mg500mg£1,139.00
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This product comes from: United States.
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Further Information

Bioactivity:
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
CAS:
1432660-47-3
Formula:
C21H18F3N3O3S2
Molecular Weight:
481.51
Pathway:
Metabolism
Purity:
0.9819
SMILES:
FC(F)(F)c1cccc(NC(=O)Nc2cc(ccc2-c2ccsc2)S(=O)(=O)NC2CC2)c1
Target:
Dehydrogenase; Isocitrate Dehydrogenase (IDH)

References

1. Wang F, et al. Science. 2013, 340(6132), 622-666. 2. Chen J, Yang J, Wei Q, et al. Cell Communication and Signaling. 2020, 18(1): 1-12. 3. Chen J, Yang J, Wei Q, et al. Identification of a selective inhibitor of IDH2/R140Q enzyme that induces cellular differentiation in leukemia cells[J]. Cell Communication and Signaling. 2020, 18: 1-12. 4. Chen J, Yang J, Wei Q, et al. Identification of a selective inhibitor of IDH2/R140Q enzyme that induces cellular differentiation in leukemia cells[J]. Cell Communication and Signaling . 2020, 18: 1-12.