TargetMol

Purmorphamine

Product Code:
 
TAR-T1810
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1810-2mg2mg£111.00
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TAR-T1810-5mg5mg£136.00
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TAR-T1810-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T1810-10mg10mg£186.00
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TAR-T1810-50mg50mg£309.00
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This product comes from: United States.
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Further Information

Bioactivity:
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo. It also is an inducer of osteoblast differentiation.
CAS:
483367-10-8
Formula:
C31H32N6O2
Molecular Weight:
520.637
Pathway:
GPCR/G Protein; Stem Cells; Autophagy
Purity:
0.9948
SMILES:
C1CCC(CC1)n1cnc2c(Nc3ccc(cc3)N3CCOCC3)nc(Oc3cccc4ccccc34)nc12
Target:
Hedgehog/Smoothened; Smo; Autophagy

References

1. Sinha S, et al. Nat Chem Biol, 2006, 2(1), 29-30. 2. Wu X, et al. J Am Chem Soc, 2002, 124(49), 14520-14521. 3. Wu X, et al. Chem Biol, 2004, 11(9), 1229-1238. 4. Faghihi F, Biomed Pharmacother, 2012, 3322(12).