TargetMol

AZ20

Product Code:
 
TAR-T1958
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1958-2mg2mg£97.00
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TAR-T1958-5mg5mg£112.00
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TAR-T1958-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T1958-10mg10mg£134.00
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TAR-T1958-25mg25mg£187.00
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TAR-T1958-50mg50mg£280.00
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TAR-T1958-100mg100mg£381.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.
CAS:
1233339-22-4
Formula:
C21H24N4O3S
Molecular Weight:
412.51
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.9802
SMILES:
C[C@@H]1COCCN1c1cc(nc(n1)-c1cccc2[nH]ccc12)C1(CC1)S(C)(=O)=O
Target:
ATM/ATR; mTOR

References

1. Xavier Jacq, et al. Cancer Res 2012;72(8 Suppl):Abstract nr 1823. 2. Foote KM, et al. J Med Chem, 2013, 56(5), 2125-2138.