TargetMol

BML-277

Product Code:
 
TAR-T2033
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2033-5mg5mg£108.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2033-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T2033-10mg10mg£132.00
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Quantity:
TAR-T2033-25mg25mg£198.00
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Quantity:
TAR-T2033-50mg50mg£325.00
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Quantity:
TAR-T2033-100mg100mg£450.00
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Quantity:
TAR-T2033-500mg500mg£863.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BML-277 is a selective checkpoint kinase 2 (Chk2) inhibitor.
CAS:
516480-79-8
Formula:
C20H14ClN3O2
Molecular Weight:
363.8
Pathway:
Cell Cycle/Checkpoint; Apoptosis
Purity:
0.997
SMILES:
NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccc(Cl)cc2)cc1
Target:
Apoptosis; Chk

References

1. Arienti KL, et al. Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles. J Med Chem. 2005 Mar 24;48(6):1873-85. 2. Liang J, Niu Z, Yu X, et al. Counteracting Genome Instability by p53-dependent Mintosis[J]. bioRxiv. 2020. 3. Liang J, Niu Z, Zhang B, et al. Liang J, Niu Z, Zhang B, et al. p53-dependent elimination of aneuploid mitotic offspring by entosis[J]. Cell Death & Differentiation. 2020: 1-15.