TargetMol

LB-100

Product Code:
 
TAR-T2068
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2068-1mg1mg£123.00
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TAR-T2068-2mg2mg£144.00
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TAR-T2068-5mg5mg£177.00
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TAR-T2068-10mg10mg£223.00
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TAR-T2068-25mg25mg£334.00
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TAR-T2068-50mg50mg£466.00
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TAR-T2068-100mg100mg£646.00
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Quantity:
TAR-T2068-500mg500mg£1,267.00
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This product comes from: United States.
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Further Information

Bioactivity:
LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation
CAS:
1026680-07-8
Formula:
C13H20N2O4
Molecular Weight:
268.313
Pathway:
Metabolism
Purity:
0.9977
SMILES:
CN1CCN(CC1)C(=O)C1C2CCC(O2)C1C(O)=O
Target:
Phosphatase

References

1. Cui J , H Wang, Medina R , et al. Inhibition of PP2A with LB-100 Enhances Efficacy of CAR-T Cell Therapy Against Glioblastoma[J]. Cancers, 2020, 12(1):139-. 2. D'Arcy B M , Swingle M R , Papke C M , et al. The Antitumor Drug LB-100 is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Catalytic Metals in the Active Site of PP5C[J]. Molecular Cancer Therapeutics, 2019.