TargetMol

CX-5461

Product Code:
 
TAR-T2100
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T2100-1mg1mg£99.00
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Quantity:
TAR-T2100-2mg2mg£108.00
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TAR-T2100-5mg5mg£149.00
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TAR-T2100-10mg10mg£201.00
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TAR-T2100-25mg25mg£304.00
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TAR-T2100-50mg50mg£466.00
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TAR-T2100-100mg100mg£646.00
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Quantity:
TAR-T2100-500mg500mg£1,251.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.
CAS:
1138549-36-6
Formula:
C27H27N7O2S
Molecular Weight:
513.62
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9801
SMILES:
CN1CCCN(CC1)c1ccc2c(n1)n1c3ccccc3sc1c(C(=O)NCc1cnc(C)cn1)c2=O
Target:
DNA/RNA Synthesis

References

1. Drygin D, et al, Cancer Res, 2011, 71(4), 1418-1430. 2. Li, Dingfeng, Juan Zhang, Ming Wang, Xiaohui Li, Huarui Gong, Huiping Tang, Lin Chen, Lili Wan, and Qiang Liu. Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation[J]. Nature communications. 2018 Apr 30;9(1):1726.