TargetMol

Trientine-2HCl

Product Code:
 
TAR-T21300
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21300-2mg2mg£102.00
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TAR-T21300-5mg5mg£117.00
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TAR-T21300-1mL1 mL * 10 mM (in DMSO)£120.00
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TAR-T21300-10mg10mg£138.00
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TAR-T21300-25mg25mg£166.00
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TAR-T21300-50mg50mg£215.00
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TAR-T21300-100mg100mg£296.00
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TAR-T21300-200mg200mg£401.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Trientine-2HCl, a chelating agent, is used to treat Wilson's disease by binding up and removing copper in the body. Trientine can also be used as a chelating agent for copper in hepatolenticular degeneration, as a stabilizer for epoxy resins, and as ampholyte for isoelectric focusing.
CAS:
38260-01-4
Formula:
C6H20Cl2N4
Molecular Weight:
219.15
Purity:
0.98
SMILES:
Cl.Cl.NCCNCCNCCN

Documents

References

1. Ala A, Aliu E, Schilsky ML. Prospective Pilot Study of a Single Daily Dosage of Trientine for the Treatment of Wilson Disease. Dig Dis Sci. 2015 Jan 21. [Epub ahead of print] PubMed PMID: 25605552. 2. Chandok N, Roberts EA. The trientine crisis in Canada: a call to advocacy. Can J Gastroenterol Hepatol. 2014 Apr;28(4):184. PubMed PMID: 24729990; PubMed Central PMCID: PMC4071922. 3. Fu S, Hou MM, Wheler J, Hong D, Naing A, Tsimberidou A, Janku F, Zinner R, Piha-Paul S, Falchook G, Kuo MT, Kurzrock R. Exploratory study of carboplatin plus the copper-lowering agent trientine in patients with advanced malignancies. Invest New Drugs. 2014 Jun;32(3):465-72. doi: 10.1007/s10637-013-0051-8. Epub 2013 Dec 5. PubMed PMID: 24306314. 4. Rezaei A, Heidarian E. Co-administration of trientine and flaxseed oil on oxidative stress, serum lipids and heart structure in diabetic rats. Indian J Exp Biol. 2013 Aug;51(8):646-52. PubMed PMID: 24228388.