TargetMol

ESI-09

Product Code:
 
TAR-T2244
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2244-2mg2mg£99.00
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TAR-T2244-5mg5mg£115.00
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TAR-T2244-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T2244-10mg10mg£142.00
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TAR-T2244-25mg25mg£213.00
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TAR-T2244-50mg50mg£328.00
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TAR-T2244-100mg100mg£458.00
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Further Information

Bioactivity:
ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.
CAS:
263707-16-0
Formula:
C16H15ClN4O2
Molecular Weight:
330.77
Pathway:
Microbiology/Virology; GPCR/G Protein
Purity:
0.9848
SMILES:
CC(C)(C)c1cc(no1)C(=O)C(=NNc1cccc(Cl)c1)C#N
Target:
cAMP; Virus Protease

References

1. Almahariq M , et al. Mol Pharmacol. 2013, 83(1), 122-128. 2. Gong B, et al. Proc Natl Acad Sci U S A. 2013, 110(48), 19615-19620. 3. Bacallao K, et al. PLoS One. 2013, 8(12), e82354. 4. Xu C, Zhao W, Huang X, et al. TORC2/3-mediated DUSP1 upregulation is essential for human decidualization[J]. Reproduction. 2021, 1(aop).