TargetMol

KenPaullone

Product Code:
 
TAR-T2247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T2247-1mg1mg£96.00
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TAR-T2247-2mg2mg£107.00
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TAR-T2247-5mg5mg£122.00
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TAR-T2247-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T2247-10mg10mg£148.00
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TAR-T2247-25mg25mg£230.00
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Quantity:
TAR-T2247-50mg50mg£340.00
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TAR-T2247-100mg100mg£470.00
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Quantity:
TAR-T2247-500mg500mg£978.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Kenpaullone, a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGFβ-Smad3 signaling pathway.
CAS:
142273-20-9
Formula:
C16H11BrN2O
Molecular Weight:
327.181
Pathway:
Cell Cycle/Checkpoint; Stem Cells; PI3K/Akt/mTOR signaling
Purity:
0.9899
SMILES:
Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Target:
GSK-3; CDK

References

1. Zaharevitz et al. Cancer Res. 1999, 59(11):2566-2569. 2. Adam COLE, et al. Biochem. J. 2004, 377(1):249-255. 3. Leclerc S, et al. J Biol Chem. 2001, 276(1):251-260. 4. Ou J, Li H, Qiu P, et al. CDK9 modulates circadian clock by attenuating REV-ERB? activity[J]. Biochemical and biophysical research communications. 2019 Jun 11;513(4):967-973.