TargetMol

Dimaprit dihydrochloride

Product Code:
 
TAR-T22724
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22724-25mg25mg£109.00
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TAR-T22724-50mg50mg£136.00
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TAR-T22724-100mg100mg£177.00
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Further Information

Bioactivity:
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.
CAS:
23256-33-9
Formula:
C6H17Cl2N3S
Molecular Weight:
234.18
Pathway:
Neuroscience; Immunology/Inflammation; GPCR/G Protein
Purity:
1
SMILES:
Cl.Cl.CN(C)CCCSC(N)=N
Target:
NOS; NO Synthase; Histamine Receptor

References

1. Parsons ME, et, al. Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology. Agents Actions. 1977 Mar; 7(1): 31-7. 2. Paquay JB, et, al. Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. Br J Pharmacol. 1999 May; 127(2): 331-4.