TargetMol

DR2313

Product Code:
 
TAR-T22749
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22749-5mg5mg£111.00
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TAR-T22749-10mg10mg£137.00
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TAR-T22749-25mg25mg£203.00
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TAR-T22749-50mg50mg£269.00
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TAR-T22749-100mg100mg£365.00
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Further Information

Bioactivity:
DR 2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.
CAS:
284028-90-6
Formula:
C8H10N2OS
Molecular Weight:
182.24
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9984
SMILES:
Cc1nc(O)c2CSCCc2n1
Target:
PARP

References

1. Nakajima H, et, al. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. J Pharmacol Exp Ther. 2005 Feb;312(2):472-81.