TargetMol

JW 67

Product Code:
 
TAR-T22884
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22884-1mg1mg£101.00
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TAR-T22884-2mg2mg£114.00
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TAR-T22884-5mg5mg£142.00
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TAR-T22884-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T22884-10mg10mg£182.00
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TAR-T22884-25mg25mg£301.00
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Quantity:
TAR-T22884-50mg50mg£442.00
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TAR-T22884-100mg100mg£618.00
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This product comes from: United States.
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Further Information

Bioactivity:
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.
CAS:
442644-28-2
Formula:
C21H18N2O6
Molecular Weight:
394.383
Pathway:
Cytoskeletal Signaling; Stem Cells
Purity:
0.98
SMILES:
O=C1Nc2ccccc2C11OCC2(CO1)COC1(OC2)C(=O)Nc2ccccc12
Target:
Wnt/beta-catenin

References

1. Waaler J, et al. Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. Cancer Res. 2011;71(1):197-205.