TargetMol

SCH442416

Product Code:
 
TAR-T23336
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23336-1mg1mg£103.00
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TAR-T23336-2mg2mg£116.00
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TAR-T23336-5mg5mg£139.00
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TAR-T23336-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T23336-10mg10mg£185.00
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TAR-T23336-25mg25mg£308.00
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TAR-T23336-50mg50mg£450.00
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TAR-T23336-100mg100mg£627.00
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Further Information

Bioactivity:
SCH-442416 is an selective antagonist of adenosine A2A receptor. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively).
CAS:
316173-57-6
Formula:
C20H19N7O2
Molecular Weight:
389.419
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9995
SMILES:
COc1ccc(CCCn2ncc3c2nc(N)n2nc(nc32)-c2ccco2)cc1
Target:
Adenosine Receptor

References

1. Kang X , Yu J , Wei Y , et al. The Effect of A 2A Receptor Antagonist (SCH 442416) on the mRNA Expression of Kir 2.1 and Kir 4.1 Channels in Rat Retinal M?ller Cells Under Hypoxic Conditions in Vitro[J]. Advances in Clinical and Experimental Medicine, 2013, 22(6):825-829. 2. Jun Yu , Yan Yan , Yiye Chen,et al. A 2A R Antagonists Upregulate Expression of GS and GLAST in Rat Hypoxia Model.Biomed Res Int. 2020 Oct 26;2020:2054293. doi: 10.1155/2020/2054293. eCollection 2020.