TargetMol

Ro-3306

Product Code:
 
TAR-T2356
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2356-1mg1mg£96.00
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TAR-T2356-5mg5mg£125.00
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TAR-T2356-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T2356-10mg10mg£145.00
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TAR-T2356-25mg25mg£197.00
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TAR-T2356-50mg50mg£254.00
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TAR-T2356-100mg100mg£369.00
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TAR-T2356-500mg500mg£768.00
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Further Information

Bioactivity:
RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases.
CAS:
872573-93-8
Formula:
C18H13N3OS2
Molecular Weight:
351.44
Pathway:
Apoptosis; Metabolism; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors; Cell Cycle/Checkpoint
Purity:
0.9974
SMILES:
O=C1N=C(NCc2cccs2)SC1=C/c1ccc2ncccc2c1
Target:
Apoptosis; ERK; SGK; PKA; CDK; PKC

References

1. Vassilev LT, et al. Proc Natl Acad Sci U S A. 2006, 103(28), 10660-10665. 2. Jang WI, et al. Anim Reprod Sci. 2014, 144(3-4), 102-108. 3. Xia Q, et al. Int J Oncol. 2014, 44(3), 735-744. 4. Ou J, Li H, Qiu P, et al. CDK9 modulates circadian clock by attenuating REV-ERB? activity[J]. Biochemical and biophysical research communications. 2019 Jun 11;513(4):967-973.