TargetMol

Adenosine N1-oxide

Product Code:
 
TAR-T23636
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23636-1mg1mg£119.00
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TAR-T23636-2mg2mg£140.00
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TAR-T23636-5mg5mg£169.00
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TAR-T23636-1mL1 mL * 10 mM (in DMSO)£172.00
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TAR-T23636-10mg10mg£213.00
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TAR-T23636-25mg25mg£327.00
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TAR-T23636-50mg50mg£436.00
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TAR-T23636-100mg100mg£608.00
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This product comes from: United States.
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Further Information

Bioactivity:
Adenosine N1-oxide, which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.
CAS:
146-92-9
Formula:
C10H13N5O5
Molecular Weight:
283.244
Pathway:
Immunology/Inflammation
Purity:
0.9924
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c1ncn(O)c2=N
Target:
Immunology/Inflammation related

References

1. Kohno K, Ohashi E, et al. Anti-inflammatory effects of adenosine N1-oxide. J Inflamm (Lond). 2015 Jan 20;12(1):2. 2. Ohashi E, Kohno K, Arai N, Harashima A, Ariyasu T, Ushio S. Adenosine N1-Oxide Exerts Anti-inflammatory Effects through the PI3K/Akt/GSK-3? Signaling Pathway and Promotes Osteogenic and Adipocyte Differentiation. Biol Pharm Bull. 2019;42(6):968-976. 3. Deng L, Dai P, Ding W, Granstein RD, Shuman S. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells. J Virol. 2006 Oct;80(20):9977-87. PubMed PMID: 17005676; PubMed Central PMCID: PMC1617288. 4. Smee DF, Sidwell RW. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. Review. PubMed PMID: 12615302.