TargetMol

GlyH-101

Product Code:
 
TAR-T2451
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2451-1mg1mg£98.00
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TAR-T2451-2mg2mg£108.00
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TAR-T2451-5mg5mg£132.00
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TAR-T2451-1mL1 mL * 10 mM (in DMSO)£139.00
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TAR-T2451-10mg10mg£168.00
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TAR-T2451-25mg25mg£279.00
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TAR-T2451-50mg50mg£486.00
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TAR-T2451-100mg100mg£653.00
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TAR-T2451-200mg200mg£838.00
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This product comes from: United States.
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Further Information

Bioactivity:
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
CAS:
328541-79-3
Formula:
C19H15Br2N3O3
Molecular Weight:
493.155
Pathway:
Membrane transporter/Ion channel; Autophagy
Purity:
0.9871
SMILES:
Oc1c(Br)cc(C=NNC(=O)CNc2ccc3ccccc3c2)c(O)c1Br
Target:
CFTR; Autophagy

References

1. Muanprasat C, et al. J Gen Physiol. 2004, 124(2), 125-137. 2. Barman PP, et al. Biochem Biophys Res Commun. 2011, 408(1), 12-17. 3. Salomon JJ, et al. Am J Physiol Lung Cell Mol Physiol. 2016. doi: 10.1152/ajplung.200321.2015. 4. Zhang, Yifei, et al. A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome [J]. Cell Reports. 2018 Aug 28;24(9):2356-2369.e5.