TargetMol

ML141

Product Code:
 
TAR-T2463
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2463-1mg1mg£97.00
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TAR-T2463-2mg2mg£107.00
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TAR-T2463-5mg5mg£124.00
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TAR-T2463-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T2463-10mg10mg£160.00
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TAR-T2463-25mg25mg£260.00
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TAR-T2463-50mg50mg£414.00
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TAR-T2463-100mg100mg£562.00
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TAR-T2463-500mg500mg£1,131.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ML141 is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
CAS:
71203-35-5
Formula:
C22H21N3O3S
Molecular Weight:
407.49
Pathway:
Cell Cycle/Checkpoint; Apoptosis; GPCR/G Protein; MAPK
Purity:
0.9977
SMILES:
COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1
Target:
Apoptosis; CDK; Ras

References

1. Surviladze Z, et al. National Center for Biotechnology Information (US); 2010. 2. Chen HY, et al. EMBO Mol Med. 2013, 5(5), 723-736. 3. Kumar A, et al. Oncotarget. 2014, 5(22), 11709-11722. 4. Hsu CR, et al. Infect Immun. 2014. pii: IAI.02345-14. 5. Chen C, et al. DOI10.1007/s12185-014-1690-z. 6. . Marcut C F. Role of action dynamics in the cooperative maintenance of synaptic plasticity[D]. 2020 7. Lv J, Zeng J, Guo F, et al. Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury[J]. Respiratory research. 2018, 19(1): 27.