TargetMol

Propargyl-PEG13-bromide

Product Code:
 
TAR-T24665
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24665-2mg2mg£132.00
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Quantity:
TAR-T24665-5mg5mg£148.00
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TAR-T24665-10mg10mg£197.00
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TAR-T24665-25mg25mg£298.00
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TAR-T24665-50mg50mg£389.00
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TAR-T24665-100mg100mg£533.00
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TAR-T24665-200mg200mg£699.00
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Quantity:
TAR-T24665-500mg500mg£1,013.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Propargyl-PEG13-bromide is a PEG derivative containing a propargyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The bromide (Br) can be used in nucleophilic substitution reactions.
CAS:
2055105-25-2
Formula:
C29H55BrO13
Molecular Weight:
691.65
Pathway:
PROTAC
Purity:
0.98
SMILES:
BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
Target:
PROTAC Linker

References

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 2. Harrison E, Coulter JA, Dixon D. Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker. Nanomedicine (Lond). 2016 Apr;11(7):851-65. Review. 3. Augusto MT, et al. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length. Molecules. 2017 Jul 15;22(7). pii: E1190. 4. Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.