TargetMol

R243

Product Code:
 
TAR-T24700
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T24700-1mg1mg£99.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-2mg2mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-5mg5mg£132.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-1mL1 mL * 10 mM (in DMSO)£140.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-10mg10mg£172.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-25mg25mg£256.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-50mg50mg£367.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24700-100mg100mg£511.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
R243 is CCR8 signaling and chemotaxis inhibitor.
CAS:
688352-84-3
Formula:
C21H27NO4
Molecular Weight:
357.45
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.9786
SMILES:
C(CN1COc2cc3OCOc3cc2C1)OC12CC3CC(CC(C3)C1)C2
Target:
CCR

References

1. Berenguer J, Lagerweij T, Zhao XW, et al. Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. J Extracell Vesicles. 2018 Mar 13;7(1):1446660. doi: 10.1080/20013078.2018.1446660. eCollection 2018. PubMed PMID: 29696074. 2. Huber DA, Schreihofer AM. Exaggerated sympathoexcitatory reflexes develop with changes in the rostral ventrolateral medulla in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R243-53. doi: 10.1152/ajpregu.00085.2016. Epub 2016 Jun 8. PubMed PMID: 27280427. 3. Wan H, Otsuka Y, Gao ZQ, Wei Y, Chen Z, Masuda M, Yonesaki T, Zhang H, Dong YH. Structural insights into the inhibition mechanism of bacterial toxin LsoA by bacteriophage antitoxin Dmd. Mol Microbiol. 2016 Sep;101(5):757-69. doi: 10.1111/mmi.13420. Epub 2016 Jun 2. PubMed PMID: 27169810. 4. Richards MB, Soares P, Torroni A. Palaeogenomics: Mitogenomes and Migrations in Europe's Past. Curr Biol. 2016 Mar 21;26(6):R243-6. doi: 10.1016/j.cub.2016.01.044. PubMed PMID: 27003890.