TargetMol

AC-90179 HCl

Product Code:
 
TAR-T26543
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26543-1mg1mg£109.00
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TAR-T26543-2mg2mg£125.00
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TAR-T26543-5mg5mg£148.00
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TAR-T26543-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T26543-10mg10mg£182.00
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TAR-T26543-25mg25mg£253.00
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TAR-T26543-50mg50mg£401.00
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TAR-T26543-100mg100mg£563.00
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Further Information

Bioactivity:
AC-90179 HCl is a selective inverse agonist of 5-HT2A receptor. AC-90179 HCl is an atypical antipsychotic pharmaceutical and has been shown to alleviate hallucinogen-induced vasocontriction.
CAS:
359878-19-6
Formula:
C23H31ClN2O2
Molecular Weight:
402.96
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9914
SMILES:
Cl.COc1ccc(CC(=O)N(Cc2ccc(C)cc2)C2CCN(C)CC2)cc1
Target:
5-HT Receptor

References

1. Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE. Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist. J Pharmacol Exp Ther. 2004 Sep;310(3):943-5Epub 2004 Apr 21. 2. Ruderman MA, Powell SB, Geyer MA. A Kappa Opioid Model of Atypical Altered Consciousness and Psychosis: U50488, DOI, AC90179 Effects on Prepulse Inhibition and Locomotion in Mice. J Young Investig. 2009 Jul 1;19(13):1-7. 3. Blessing WW, Seaman B. 5-hydroxytryptamine(2A) receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats. Neuroscience. 2003;117(4):939-48. 4. Weiner DM, Burstein ES, Nash N, Croston GE, Currier EA, Vanover KE, Harvey SC, Donohue E, Hansen HC, Andersson CM, Spalding TA, Gibson DF, Krebs-Thomson K, Powell SB, Geyer MA, Hacksell U, Brann MR. 5-hydroxytryptamine2A receptor inverse agonists as antipsychotics. J Pharmacol Exp Ther. 2001 Oct;299(1):268-76.