TargetMol

BMS 777607

Product Code:
 
TAR-T2699
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2699-1mg1mg£96.00
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TAR-T2699-2mg2mg£107.00
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TAR-T2699-5mg5mg£128.00
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TAR-T2699-1mL1 mL * 10 mM (in DMSO)£138.00
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TAR-T2699-10mg10mg£172.00
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TAR-T2699-25mg25mg£254.00
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TAR-T2699-50mg50mg£374.00
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TAR-T2699-100mg100mg£522.00
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Further Information

Bioactivity:
BMS-777607 is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
CAS:
1025720-94-8
Formula:
C25H19ClF2N4O4
Molecular Weight:
512.89
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9989
SMILES:
CCOc1c(C(=O)Nc2cc(F)c(Oc3c(Cl)c(N)ncc3)cc2)c(=O)n(cc1)c1ccc(F)cc1
Target:
c-Met/HGFR; TAM Receptor

References

1. Schroeder GM, et al. J Med Chem, 2009, 52(5), 1251-1254. 2. Dai Y, et al. Mol Cancer Ther, 2010, 9(6), 1554-1561. 3. Dai Y, et al. Clin Exp Metastasis, 2012, 29, 253-261. 4. Kim KS, et al. J Med Chem, 2008, 51(17), 5330-5341.