TargetMol

Coralyne chloride

Product Code:
 
TAR-T31011
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31011-1mg1mg£96.00
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TAR-T31011-2mg2mg£107.00
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TAR-T31011-5mg5mg£128.00
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TAR-T31011-10mg10mg£173.00
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TAR-T31011-25mg25mg£303.00
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TAR-T31011-50mg50mg£436.00
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TAR-T31011-100mg100mg£610.00
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This product comes from: United States.
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Further Information

Bioactivity:
Coralyne chloride is a molecular rectifier based on fluorescent DNA, which is constructed into DNA double-stranded bodies by site-specific insertion.
CAS:
38989-38-7
Formula:
C22H22ClNO4
Molecular Weight:
399.87
Pathway:
DNA Damage/DNA Repair
Purity:
0.9935
SMILES:
[Cl-].COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC
Target:
Topoisomerase

References

1. Khadka DB, Cho WJ. Topoisomerase inhibitors as anticancer agents: a patent update. Expert Opin Ther Pat. 2013 Aug;23(8):1033-56. 2. Seema Kumari, et al. Synergistic effects of coralyne and paclitaxel on cell migration and proliferation of breast cancer cells lines. Biomed Pharmacother. 2017 Jul;91:436-445. 3. Bhadra K, Kumar GS. Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design. Med Res Rev. 2011 Nov;31(6):821-62. 4. Giri P, Suresh Kumar G. Molecular recognition of poly(A) targeting by protoberberine alkaloids: in vitro biophysical studies and biological perspectives. Mol Biosyst. 2010 Jan;6(1):81-8.