TargetMol

IDE1

Product Code:
 
TAR-T3162
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T3162-1mg1mg£105.00
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TAR-T3162-2mg2mg£119.00
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TAR-T3162-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T3162-5mg5mg£143.00
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TAR-T3162-10mg10mg£191.00
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TAR-T3162-25mg25mg£328.00
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TAR-T3162-50mg50mg£458.00
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TAR-T3162-100mg100mg£626.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-β signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.
CAS:
1160927-48-9
Formula:
C15H18N2O5
Molecular Weight:
306.318
Purity:
0.9836
SMILES:
OC(=O)CCCCCC(=O)NN=Cc1ccccc1C(O)=O

References

1. Hoveizi E, et al. Definitive endoderm differentiation of human-induced pluripotent stem cells using signaling molecules and IDE1 in three-dimensional polymer scaffold. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.