TargetMol

ISCK03

Product Code:
 
TAR-T3452
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3452-2mg2mg£97.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T3452-5mg5mg£112.00
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Quantity:
TAR-T3452-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T3452-10mg10mg£139.00
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TAR-T3452-25mg25mg£217.00
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TAR-T3452-50mg50mg£321.00
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Quantity:
TAR-T3452-100mg100mg£497.00
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This product comes from: United States.
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Further Information

Bioactivity:
ISCK03 is a selective SCF/c-Kit inhibitor.
CAS:
945526-43-2
Formula:
C19H21N3O2S
Molecular Weight:
355.46
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9823
SMILES:
CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-n1ccnc1
Target:
c-Kit

References

Na YJ, et al. [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. Biochem Pharmacol. 2007 Sep 1;74(5):780-6. Hirano T, et al. Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression. Mol Cancer. 2015 Apr 19;14:90. doi: 10.1186/s12943-015-0364-7.