TargetMol

CPI-455

Product Code:
 
TAR-T3552
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3552-1mg1mg£100.00
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TAR-T3552-2mg2mg£111.00
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TAR-T3552-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T3552-5mg5mg£134.00
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TAR-T3552-10mg10mg£177.00
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TAR-T3552-25mg25mg£310.00
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Quantity:
TAR-T3552-50mg50mg£511.00
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TAR-T3552-100mg100mg£704.00
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Quantity:
TAR-T3552-500mg500mg£1,380.00
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This product comes from: United States.
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Further Information

Bioactivity:
CPI-455 is a specific KDM5 inhibitor.
CAS:
1628208-23-0
Formula:
C16H14N4O
Molecular Weight:
278.315
Pathway:
Chromatin/Epigenetic
Purity:
0.9902
SMILES:
CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
Target:
Histone Demethylase

References

Vinogradova M, et al. Nat Chem Biol. 2016, 12(7):531-8. Shen X, Ye Z, Wu W, et al. lncRNA NEAT1 facilitates the progression of colorectal cancer via the KDM5A/Cul4A and Wnt signaling pathway. International Journal of Oncology. 2021, 59(1): 1-12. Li S T, Huang D, Shen S, et al. Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis. Nature Metabolism. 2020, 2(3): 256-269 Li S T, Huang D, Shen S, et al. Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis[J]. Nature Metabolism. 2020, 2(3): 256-269.