TargetMol

BGP-15

Product Code:
 
TAR-T3649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T3649-2mg2mg£101.00
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TAR-T3649-5mg5mg£119.00
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TAR-T3649-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T3649-10mg10mg£152.00
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TAR-T3649-25mg25mg£230.00
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TAR-T3649-50mg50mg£367.00
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TAR-T3649-100mg100mg£455.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BGP-15 is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.
CAS:
66611-37-8
Formula:
C14H24Cl2N4O2
Molecular Weight:
351.27
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9989
SMILES:
Cl.Cl.NC(=N/OCC(O)CN1CCCCC1)c1cccnc1
Target:
PARP

References

Salah H, et al. The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction. Sci Transl Med. 2016 Aug 3;8(350):350ra10 Chung J, et al. Proc Natl Acad Sci U S A. 2008, 105(5):1739-44. Racz I, et al. Biochem Pharmacol. 2002, 63(6):1099-111. Sarszegi Z, et al. Mol Cell Biochem. 2012, 365(1-2):129-37. Sapra G, et al. Nat Commun. 2014, 5:5705.