TargetMol

CAY10781

Product Code:
 
TAR-T37424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37424-1mg1mg£105.00
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TAR-T37424-2mg2mg£118.00
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TAR-T37424-5mg5mg£140.00
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TAR-T37424-10mg10mg£169.00
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TAR-T37424-1mL1 mL * 10 mM (in DMSO)£172.00
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TAR-T37424-25mg25mg£249.00
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TAR-T37424-50mg50mg£325.00
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TAR-T37424-100mg100mg£542.00
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TAR-T37424-500mg500mg£1,099.00
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Further Information

Bioactivity:
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
CAS:
1210360-87-4
Formula:
C11H9N3O3
Molecular Weight:
231.211
Purity:
0.98
SMILES:
OC(=O)Cc1cnc([nH]c1=O)-c1cccnc1

References

Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)