TargetMol

Alamandine TFA

Product Code:
 
TAR-T37496L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T37496L-1mg1mg£115.00
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Quantity:
TAR-T37496L-2mg2mg£133.00
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TAR-T37496L-5mg5mg£161.00
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TAR-T37496L-10mg10mg£213.00
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TAR-T37496L-25mg25mg£354.00
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Quantity:
TAR-T37496L-50mg50mg£498.00
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Quantity:
TAR-T37496L-100mg100mg£688.00
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Quantity:
TAR-T37496L-500mg500mg£1,340.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Alamandine TFA , a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine TFA targets to protect the kidney and heart through anti-hypertensive actions[1][2].
CAS:
T37496L
Formula:
C42H63F3N12O11
Molecular Weight:
969.02
Pathway:
Endocrinology/Hormones
Purity:
0.9962
SMILES:
OC(C(F)(F)F)=O.O=C(O)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)CCC1
Target:
RAAS

References

Johanna Schleifenbaum. Alamandine and Its Receptor MrgD Pair Up to Join the Protective Arm of the Renin-Angiotensin System. Front Med (Lausanne). 2019 Jun 11;6:107. Chi Liu, et al. Alamandine attenuates hypertension and cardiac hypertrophy in hypertensive rats. Amino Acids. 2018 Aug;50(8):1071-1081. Daniel C Villela, et al. Alamandine: a new member of the angiotensin family. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):130-4.