TargetMol

11-cis Retinal

Product Code:
 
TAR-T38219
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38219-2mg2mgEnquire
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Further Information

Bioactivity:
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.
CAS:
564-87-4
Formula:
C20H28O
Molecular Weight:
284.443
Purity:
0.98
SMILES:
C/C(/C=CC=C(/C)C=CC1=C(C)CCCC1(C)C)=CC=O