TargetMol

GSK717

Product Code:
 
TAR-T38361
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38361-1mg1mg£103.00
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TAR-T38361-2mg2mg£118.00
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TAR-T38361-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T38361-5mg5mg£148.00
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TAR-T38361-10mg10mg£189.00
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TAR-T38361-25mg25mg£287.00
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Quantity:
TAR-T38361-50mg50mg£434.00
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This product comes from: United States.
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Further Information

Bioactivity:
GSK717 is a potent and selective inhibitor of nucleotide-binding oligomerization domain 2 (NOD2). GSK717 blocks synergy between NOD2 and TLR2. GSK717 does not affect NOD1, TNFR1 and TLR2-mediated responses.
CAS:
1595278-21-9
Formula:
C28H28N4O2
Molecular Weight:
452.55
Pathway:
NF-κb; Immunology/Inflammation
Purity:
0.9901
SMILES:
O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O
Target:
IL Receptor; NOD

References

Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.