TargetMol

Esculentoside A

Product Code:
 
TAR-T3877
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3877-1mg1mg£95.00
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TAR-T3877-5mg5mg£122.00
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TAR-T3877-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T3877-10mg10mg£161.00
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TAR-T3877-25mg25mg£242.00
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TAR-T3877-50mg50mg£327.00
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TAR-T3877-100mg100mg£452.00
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Further Information

Bioactivity:
Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmune disease through modulation on T cell-mediated adaptive immunity. Esculentoside A may play significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis.
CAS:
65497-07-6
Formula:
C42H66O16
Molecular Weight:
826.974
Pathway:
NF-κb; Neuroscience; Immunology/Inflammation
Purity:
0.9981
SMILES:
COC(=O)[C@@]1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6OC[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
Target:
NF-κB; COX

References

Ma H,et al. The effect of esculentoside A on lupus nephritis-prone BXSB mice. Arch Med Sci. 2013 Apr 20;9(2):354-60. Zhong WT,et al. Protective effect of esculentoside A on lipopolysaccharide-induced acute lung injury in mice. J Surg Res. 2013 Nov;185(1):364-72.