TargetMol

9-amino-CPT

Product Code:
 
TAR-T3S1957
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3S1957-1mg1mg£99.00
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TAR-T3S1957-2mg2mg£109.00
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TAR-T3S1957-5mg5mg£145.00
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TAR-T3S1957-10mg10mg£189.00
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TAR-T3S1957-25mg25mg£282.00
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TAR-T3S1957-50mg50mg£386.00
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TAR-T3S1957-100mg100mg£533.00
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This product comes from: United States.
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Further Information

Bioactivity:
9-Aminocamptothecin is an inhibitor of topoisomerase I with potent anticancer activity.
CAS:
91421-43-1
Formula:
C20H17N3O4
Molecular Weight:
363.4
Pathway:
DNA Damage/DNA Repair
Purity:
0.9982
SMILES:
CC[C@](C(C=C(c1nc2ccc3)N4Cc1cc2c3N)=C(CO1)C4=O)(C1=O)O
Target:
Topoisomerase

References

Jeha S, et al. Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia. Leuk Lymphoma. 1998 Dec;32(1-2):159-64. Li ML, et al. Pharmacological determinants of 9-aminocamptothecin cytotoxicity. Clin Cancer Res. 2001 Jan;7(1):168-74. de Souza PL, et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate cancer. Clin Cancer Res. 1997 Feb;3(2):287-94.