TargetMol

Selamectin

Product Code:
 
TAR-T4059
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4059-2mg2mg£95.00
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TAR-T4059-5mg5mg£111.00
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TAR-T4059-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T4059-10mg10mg£138.00
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TAR-T4059-25mg25mg£213.00
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TAR-T4059-50mg50mg£309.00
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TAR-T4059-100mg100mg£454.00
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TAR-T4059-500mg500mg£914.00
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This product comes from: United States.
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Further Information

Bioactivity:
Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition.
CAS:
220119-17-5
Formula:
C43H63NO11
Molecular Weight:
769.973
Pathway:
Microbiology/Virology; Membrane transporter/Ion channel; Neuroscience
Purity:
1
SMILES:
CO[C@H]1C[C@H](O[C@H]2[C@@H](C)C=CC=C3/CO[C@@H]4C(=NO)C(C)=C[C@@H](C(=O)O[C@H]5C[C@@H](CC=C2/C)O[C@@]2(CC[C@H](C)[C@H](O2)C2CCCCC2)C5)[C@]34O)O[C@@H](C)[C@@H]1O
Target:
Chloride channel; P-gp; Parasite

References

Holden-Dye, L. , et al. Anthelmintic drugs and nematicides: Studies in Caenorhabditis elegans. WormBook 16, (2014). Michael, B.,et al. Comparison of ivermectin, doramectin, selamectin, and eleven intermediates in a nematode larval development assay. Journal of Parasitology 87(3), 692-696 (2001).