TargetMol

Leonurine hydrochloride

Product Code:
 
TAR-T4080
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4080-5mg5mg£114.00
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TAR-T4080-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T4080-10mg10mg£136.00
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This product comes from: United States.
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Further Information

Bioactivity:
Leonurine (hydrochloride), a major alkaloid compound extracted from Leonurus japonicas Houtt. (Labiatae), is considered to have antitumor roles.
CAS:
24735-18-0
Formula:
C14H22ClN3O5
Molecular Weight:
347.79
Pathway:
Immunology/Inflammation; Autophagy
Purity:
1
SMILES:
Cl.COc1cc(cc(OC)c1O)C(=O)OCCCCNC(N)=N
Target:
TLR; Autophagy

References

Li X, et al. Effect of leonurine hydrochloride on endothelin and the endothelin receptor-mediated signal pathway in medically-induced incomplete abortion in rats. Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(2):299-303. Yuan, F., Xu, R., Jiang, D., He, X., Su, Q., Jin, C., & Li, X. (2015). Leonurine hydrochloride inhibits osteoclastogenesis and prevents osteoporosis associated with estrogen deficiency by inhibiting the NF-?B and PI3K/Akt signaling pathways.?Bone,?75, 128-137. doi: 10.1016/j.bone.2015.02.017 Mao F, et al. Leonurine hydrochloride induces apoptosis of H292 lung cancer cell by a mitochondria-dependent pathway. Pharm Biol. 2015;53(11):1684-90. Li X, et al. Effects of leonurine hydrochloride on medically induced incomplete abortion in early pregnancy rats. Eur J Obstet Gynecol Reprod Biol. 2011 Dec;159(2):375-80.