TargetMol

MK-8617

Product Code:
 
TAR-T4106
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4106-1mg1mg£95.00
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TAR-T4106-2mg2mg£103.00
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TAR-T4106-5mg5mg£122.00
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TAR-T4106-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-T4106-10mg10mg£142.00
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TAR-T4106-25mg25mg£209.00
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TAR-T4106-50mg50mg£333.00
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TAR-T4106-100mg100mg£461.00
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TAR-T4106-200mg200mg£627.00
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TAR-T4106-500mg500mg£946.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).
CAS:
1187990-87-9
Formula:
C24H21N5O4
Molecular Weight:
443.463
Pathway:
Chromatin/Epigenetic; Metabolism
Purity:
0.9963
SMILES:
COc1ccc(cc1)C(NC(=O)c1cnc([nH]c1=O)-c1cccnn1)c1ccc(OC)cc1
Target:
HIF/HIF Prolyl-Hydroxylase

References

John S. Debenham, et al. J Med Chem. 2016, 59 (24):11039-11049.