TargetMol

lavendustin B

Product Code:
 
TAR-T4182
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4182-1mg1mg£115.00
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TAR-T4182-2mg2mg£134.00
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TAR-T4182-5mg5mg£168.00
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TAR-T4182-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T4182-10mg10mg£230.00
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TAR-T4182-25mg25mg£430.00
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TAR-T4182-50mg50mg£599.00
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TAR-T4182-100mg100mg£824.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).
CAS:
125697-91-8
Formula:
C21H19NO5
Molecular Weight:
365.385
Pathway:
Proteases/Proteasome; Metabolism; Microbiology/Virology
Purity:
0.9572
SMILES:
OC(=O)c1cc(ccc1O)N(Cc1ccccc1O)Cc1ccccc1O
Target:
Tyrosinase; transporter; HIV Protease

References

Agharbaoui FE, et al. Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase. Eur J Med Chem. 2016 Nov 10;123:673-83 Alioua A,et al. Coupling of c-Src to large conductance voltage- and Ca2+-activated K+ channels as a new mechanism of agonist-induced vasoconstriction. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14560-5 Fujii E, et al. Role of nitric oxide, prostaglandins and tyrosine kinase in vascular endothelial growth factor-induced increase in vascular permeability in mouse skin. Naunyn Schmiedebergs Arch Pharmacol. 1997 Oct;356(4):475-80