TargetMol

Avibactam sodium

Product Code:
 
TAR-T4201
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4201-2mg2mg£99.00
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TAR-T4201-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T4201-5mg5mg£115.00
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TAR-T4201-10mg10mg£132.00
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TAR-T4201-25mg25mg£145.00
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TAR-T4201-50mg50mg£173.00
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Quantity:
TAR-T4201-100mg100mg£221.00
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TAR-T4201-200mg200mg£277.00
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Quantity:
TAR-T4201-500mg500mg£420.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Avibactam is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).
CAS:
1192491-61-4
Formula:
C7H10N3NaO6S
Molecular Weight:
287.22
Pathway:
Microbiology/Virology
Purity:
0.9916
SMILES:
[Na+].NC(=O)C1CCC2CN1C(=O)N2OS([O-])(=O)=O
Target:
Antibacterial; Antibiotic

References

Livermore DM, et al. Characterization of ?-lactamase and porin mutants of Enterobacteriaceae selected with ceftaroline + avibactam (NXL104). J Antimicrob Chemother. 2012 Jun;67(6):1354-8. Ehmann DE, et al. Avibactam is a covalent, reversible, non-?-lactam ?-lactamase inhibitor. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11663-8. Berkhout J, et al. Pharmacokinetics and penetration of ceftazidime and avibactam into epithelial lining fluid in thigh- and lung-infected mice. Antimicrob Agents Chemother. 2015 Apr;59(4):2299-304.