TargetMol

Succinobucol

Product Code:
 
TAR-T4287
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4287-5mg5mg£108.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T4287-1mL1 mL * 10 mM (in DMSO)£122.00
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Quantity:
TAR-T4287-10mg10mg£135.00
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Quantity:
TAR-T4287-25mg25mg£201.00
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Quantity:
TAR-T4287-50mg50mg£294.00
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Quantity:
TAR-T4287-100mg100mg£453.00
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Quantity:
TAR-T4287-500mg500mg£914.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Succinobucol is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary artery disease.
CAS:
216167-82-7
Formula:
C35H52O5S2
Molecular Weight:
616.92
Pathway:
oxidation-reduction; NF-κb; Metabolism; Immunology/Inflammation
Purity:
0.9996
SMILES:
CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(OC(=O)CCC(O)=O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C
Target:
Antioxidant; Reactive Oxygen Species

References

Colle D, et al. Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity. Mol Neurobiol. 2016 Mar;53(2):1280-95. Houston SA, et al. An investigation of the antiplatelet effects of succinobucol (AGI-1067). Platelets. 2017 May;28(3):295-300 Dan Z, et al. A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer. Theranostics. 2016 Jan 25;6(3):435-45.