TargetMol

Preladenant

Product Code:
 
TAR-T4290
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4290-1mg1mg£98.00
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TAR-T4290-2mg2mg£109.00
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TAR-T4290-5mg5mg£132.00
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TAR-T4290-10mg10mg£172.00
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TAR-T4290-25mg25mg£250.00
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TAR-T4290-50mg50mg£367.00
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TAR-T4290-100mg100mg£511.00
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Quantity:
TAR-T4290-500mg500mg£1,026.00
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This product comes from: United States.
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Further Information

Bioactivity:
Preladenant is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosine receptors.
CAS:
377727-87-2
Formula:
C25H29N9O3
Molecular Weight:
503.567
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9818
SMILES:
COCCOc1ccc(cc1)N1CCN(CCn2ncc3c2nc(N)n2nc(nc32)-c2ccco2)CC1
Target:
Adenosine Receptor

References

Hodgson RA, et al. Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression. J Pharmacol Exp Ther. 2009 Jul;330(1):294-303. Hodgson RA, et al. Preladenant, a selective A(2A) receptor antagonist, is active in primate models of movement disorders. Exp Neurol. 2010 Oct;225(2):384-90.