TargetMol

YU238259

Product Code:
 
TAR-T4339
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4339-1mg1mg£103.00
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TAR-T4339-2mg2mg£116.00
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TAR-T4339-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T4339-5mg5mg£142.00
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TAR-T4339-10mg10mg£195.00
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TAR-T4339-25mg25mg£329.00
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TAR-T4339-50mg50mg£530.00
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TAR-T4339-100mg100mg£731.00
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TAR-T4339-500mg500mg£1,428.00
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Further Information

Bioactivity:
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.
CAS:
1943733-16-1
Formula:
C22H22ClN3O4S
Molecular Weight:
459.95
Pathway:
DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling;
Purity:
0.9943
SMILES:
COc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCCc1ccc(Cl)cn1
Target:
DNA-PK;

References

Stachelek GC,etal.YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.Mol Cancer Res. 2015 Oct;13(10):1389-97.