TargetMol

Eprenetapopt

Product Code:
 
TAR-T4414
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4414-5mg5mg£124.00
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TAR-T4414-1mL1 mL * 10 mM (in DMSO)£130.00
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TAR-T4414-10mg10mg£156.00
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TAR-T4414-25mg25mg£245.00
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TAR-T4414-50mg50mg£381.00
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TAR-T4414-100mg100mg£622.00
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Quantity:
TAR-T4414-500mg500mg£1,187.00
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Further Information

Bioactivity:
PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
CAS:
5291-32-7
Formula:
C10H17NO3
Molecular Weight:
199.25
Pathway:
Apoptosis; Cell Cycle/Checkpoint; Autophagy;
Purity:
0.9957
SMILES:
COCC1(CO)N2CCC(CC2)C1=O
Target:
Apoptosis; Ferroptosis; p53; Autophagy

References

Peng X,etal.APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.Cell Death Dis. 2013 Oct 24;4:e881. Stuber G,etal.PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein.Mol Cancer. 2009 Mar 26;8:23.