TargetMol

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Product Code:
 
TAR-T4460
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4460-5mg5mg£105.00
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TAR-T4460-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T4460-10mg10mg£119.00
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TAR-T4460-25mg25mg£130.00
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TAR-T4460-50mg50mg£145.00
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TAR-T4460-100mg100mg£164.00
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Quantity:
TAR-T4460-500mg500mg£298.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dapagliflozin (2S)-1, 2-propanediol, hydrate is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
CAS:
960404-48-2
Formula:
C24H35ClO9
Molecular Weight:
502.99
Pathway:
GPCR/G Protein
Purity:
0.9994
SMILES:
O.C[C@H](O)CO.CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
Target:
SGLT

References

Vivian EM.etal.Dapagliflozin: a new sodium-glucose cotransporter 2 inhibitor for treatment of type 2 diabetes.Am J Health Syst Pharm. 2015 Mar 1;72(5):361-72. Plosker GL.etal.Dapagliflozin: a review of its use in type 2 diabetes mellitus.Drugs. 2012 Dec 3;72(17):2289-312.