TargetMol

Pyridostatin TFA

Product Code:
 
TAR-T4470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4470-1mg1mg£99.00
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TAR-T4470-2mg2mg£108.00
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TAR-T4470-5mg5mg£130.00
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TAR-T4470-10mg10mg£161.00
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TAR-T4470-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T4470-25mg25mg£232.00
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TAR-T4470-50mg50mg£315.00
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TAR-T4470-100mg100mg£483.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.
CAS:
1472611-44-1
Formula:
C37H35F9N8O11
Molecular Weight:
938.718
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9984
SMILES:
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1
Target:
DNA/RNA Synthesis

References

Rodriguez R,etal. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.Nat Chem Biol. 2012 Feb 5;8(3):301-10. Murat P,etal.G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation.Nat Chem Biol. 2014 May;10(5):358-64. Koirala D,etal.A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.Nat Chem. 2011 Aug 28;3(10):782-7.