TargetMol

Tapinarof

Product Code:
 
TAR-T4644
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4644-1mg1mg£98.00
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TAR-T4644-2mg2mg£109.00
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TAR-T4644-5mg5mg£132.00
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TAR-T4644-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T4644-10mg10mg£172.00
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TAR-T4644-25mg25mg£266.00
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TAR-T4644-50mg50mg£367.00
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TAR-T4644-100mg100mg£511.00
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Quantity:
TAR-T4644-500mg500mg£1,026.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
CAS:
79338-84-4
Formula:
C17H18O2
Molecular Weight:
254.329
Pathway:
Metabolism; Immunology/Inflammation
Purity:
0.9984
SMILES:
CC(C)c1c(O)cc(C=Cc2ccccc2)cc1O
Target:
AhR; Aryl Hydrocarbon Receptor

References

Han Q, Chen H, Wang L, et al. Systemic Deficiency of GHR in Pigs leads to Hepatic Steatosis via Negative Regulation of AHR Signaling. International Journal of Biological Sciences. 2021, 17(15): 4108-4121. Sun Y, Chen L H, Wang H X, et al. Activation of aryl hydrocarbon receptor ameliorates rosacea-like eruptions in mice and suppresses the TLR signaling pathway in LL-37-induced HaCaT cells. Toxicology and Applied Pharmacology. 2022: 116189. Smith SH, et al. Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans. J Invest Dermatol. 2017 Oct;137(10):2110-2119.