TargetMol

RAD51 Inhibitor B02

Product Code:
 
TAR-T4656
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4656-2mg2mg£103.00
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TAR-T4656-5mg5mg£124.00
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TAR-T4656-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T4656-10mg10mg£149.00
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TAR-T4656-25mg25mg£207.00
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TAR-T4656-50mg50mg£293.00
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TAR-T4656-100mg100mg£438.00
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This product comes from: United States.
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Further Information

Bioactivity:
RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.
CAS:
1290541-46-6
Formula:
C22H17N3O
Molecular Weight:
339.398
Pathway:
Apoptosis; DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.999
SMILES:
O=c1n(Cc2ccccc2)c(C=Cc2cccnc2)nc2ccccc12
Target:
Apoptosis; DNA/RNA Synthesis

References

Huang F, et al. A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts. PLoS One. 2014 Jun 27;9(6):e100993. Huang F, et al. Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening. ACS Chem Biol. 2011 Jun 17;6(6):628-35.