TargetMol

Tetrahydroxystilbene-2-O-β-D-glucoside

Product Code:
 
TAR-T4956
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T4956-1mg1mg£125.00
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TAR-T4956-5mg5mg£199.00
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TAR-T4956-1mL1 mL * 10 mM (in DMSO)£215.00
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TAR-T4956-10mg10mg£271.00
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TAR-T4956-25mg25mg£406.00
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TAR-T4956-50mg50mg£571.00
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TAR-T4956-100mg100mg£783.00
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TAR-T4956-500mg500mg£1,500.00
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Further Information

Bioactivity:
Tetrahydroxystilbene-2-O-β-D-glucoside is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.
CAS:
55327-45-2
Formula:
C20H22O9
Molecular Weight:
406.38
Purity:
0.98
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@H]([C@@H]1O)O)O)Oc2c(C=Cc3ccc(O)cc3)cc(O)cc2O

References

Activating mitochondrial function and haemoglobin expression with EH?201, an inducer of erythropoietin in neuronal cells, reverses memory impairment[J]. British Journal of Pharmacology, 2015, 172(19):4741-4756.