TargetMol

Cinobufotalin

Product Code:
 
TAR-T4A2399
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4A2399-50mg50mgEnquire
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TAR-T4A2399-1mg1mg£106.00
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TAR-T4A2399-2mg2mg£120.00
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TAR-T4A2399-5mg5mg£142.00
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TAR-T4A2399-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T4A2399-10mg10mg£191.00
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TAR-T4A2399-25mg25mg£272.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent for the multidrug resistance of tumors, it can reverse the adriamycin-resistance in Raji/ADR cells and the expression of P-gp and MRP-1 proteins. Cinobufotalin can promote the dendritic cells(DCs) derived from peripheral blood of patients with chronic hepatitis B to mature and effectively enhance its(the DCs') capabilities, therefore the treatment of cinobufotalin may potentiate the antiviral immunity of the patients with chronic hepatitis B(CHB).
CAS:
1108-68-5
Formula:
C26H34O7
Molecular Weight:
458.551
Pathway:
Immunology/Inflammation; Cytoskeletal Signaling; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
Purity:
0.9994
SMILES:
CC(=O)O[C@H]1[C@H]2O[C@]22[C@@H]3CC[C@]4(O)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@H]1c1ccc(=O)oc1
Target:
IL Receptor; Akt; MRP; P-gp