TargetMol

Prostaglandin E2

Product Code:
 
TAR-T5014
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5014-2mg2mg£109.00
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TAR-T5014-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T5014-5mg5mg£125.00
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TAR-T5014-10mg10mg£146.00
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TAR-T5014-25mg25mg£229.00
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Quantity:
TAR-T5014-50mg50mg£375.00
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Quantity:
TAR-T5014-100mg100mg£544.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
CAS:
363-24-6
Formula:
C20H32O5
Molecular Weight:
352.471
Pathway:
Metabolism; Immunology/Inflammation; GPCR/G Protein
Purity:
0.9995
SMILES:
CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CC=C/CCCC(O)=O
Target:
Endogenous Metabolite; Prostaglandin Receptor

References

Wang M, Wang X, Jiang B, et al. Identification of MRAP protein family as broad?spectrum GPCR modulators. Clinical and Translational Medicine. 2022, 12(11): e1091. Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132(4):1851-7. Haylor J, et al. Renal vasodilator activity of prostaglandin E2 in the rat anaesthetized with pentobarbitone. Br J Pharmacol. 1982 May;76(1):131-7. Fernandez-Repollet E, et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70. Chen S, Wu Y, Gao Y, et al.Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness.Cell Reports.2023, 42(10): 113246. Tang C, Sun H, Kadoki M, et al.Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.Nature Communications.2023, 14(1): 1493.